Chemists are the architects of matter. Chemists design, build, and probe matter spanning multiple length-scales, from molecules and atomic clusters, to macro-molecular assemblies and crystalline solids. A crucial result of these efforts is that chemists can draw explicit links between the structure and composition of matter and its attendant physical properties. These links establish fundamental insight into the static and dynamic responses of matter to electromagnetic stimuli and also define the nature of matter-matter interactions, which determine the reactivity of species. Aside from its role as one of the core sciences, chemistry is at the heart of technology that has transformed industry and society.