The Ephraim and Wilma Shaw Roseman Seminar Series presents Michael Freeman
The Ephraim and Wilma Shaw Roseman Seminar Series presents Michael Freeman
Professor Michael Freeman, University of Minnesota “Biosynthetic insights into α-N-methylated peptide natural products” Ribosomally synthesized and post-translationally modified peptides (RiPPs) provide biosynthetic routes to peptide modifications not often observed in primary metabolism. We have recently discovered RiPP pathways that install peptide backbone α-N-methylations conferring therapeutically useful peptide properties including membrane permeability, increased target specificity, and […]