Professor Leah Dodson
Remsen Hall 233Professor Leah Dodson, University of Maryland, College Park Abstract and bio to come.
Professor Leah Dodson, University of Maryland, College Park Abstract and bio to come.
“Building efficient and transferable generative models of intrinsically disordered protein conformational ensembles” Professor Grant M. Rotskoff, Stanford University ABSTRACT: Nearly half of the proteome is intrinsically disordered, consisting of proteins or motifs that lack a stable secondary structure. Modeling these regions remains challenging, even with tremendous advances in generative models for protein structure prediction. Sampling […]
Christy Landes, University of Illinois Urbana-Champaign "Towards predictive protein separations: Imaging protein dynamics at nanoscale interfaces" Abstract: Recent efforts by our group and others have shown the promise of applying single molecule methods to link mechanistic detail about protein adsorption to macroscale observables. When we study one molecule at a time, we eliminate ensemble averaging, […]
Mingxuan Wu, Westlake University "Development of sulfonium and diazonium tools to investigate lysine methylation" Abstract: Lysine methylation is a posttranslational modification (PTM) that regulates many cellular processes. For example, histone H3K27 methylation leads to gene silence as an important type of epigenetic marks. Hypermethylation of histone H3K27 may drive cancer and the methyltransferase EZH2 is […]
Professor Christian R. Goldsmith, Auburn University "Using Transition Metal Complexes with Quinol-Containing Ligands to Image and Treat Oxidative Stress" Abstract: Oxidative stress has been linked to a wide variety of lethal and debilitating health conditions. The lack of sensors capable of imaging in vivo oxidative stress, however, precludes us from fully understanding what roles reactive […]
Katherine Franz, Duke University "Infectiously Inorganic: A Metallocentric View of Antimicrobial Activity" Abstract: Normal and pathogenic cells require a menu of metal nutrients for optimal growth, but also strategies to mitigate toxicity associated with misregulated or excessive levels of metals like Fe, Cu and Zn. Cells adjust metal homeostasis mechanisms depending on cell type, local […]
Carsten Milsmann, University of Delaware "Earth-Abundant Elements in a New Light: Photophysics and Photochemistry of Early Transition Metal Photosensitizers" Abstract: Advances in chemical control of the photophysical properties of transition metal complexes are revolutionizing a wide range of technologies, such as photocatalysis, solar energy conversion, and lightemitting diodes, but rely heavily on molecules containing precious […]
Vincent Ortiz, Auburn University "New-Generation Electron-Propagator Concepts in Chemical Bonding Theory" Abstract: Chemists have a long history of explaining trends in bonding, spectra and reactivity in terms of molecular orbital (MO) concepts. Whereas MO theories began as qualitative tools of pattern recognition and prediction, they have been supplanted by related concepts with quantitative aspirations. Ab […]
Jennifer Bridwell-Rabb, University of Michigan "Design Principles for Metalloprotein Chemistry" Abstract: Metalloproteins catalyze some of Nature’s most amazing and difficult chemical transformations. One such transformation, of interest to our laboratory, is the use of a high valent Fe-based oxidant to facilitate the functionalization of a traditionally inert C–H bond. Since this chemistry is vital to […]
David Beratan, Duke University "To be Announced" Abstract: To be Announced
Huan-Xiang Zhou, University of Illinois Chicago "To be Announced" Abstract: To be Announced
Yogesh Surendranath, Massachusetts Institute of Technology "Using Electrochemistry to Understand and Control Sustainable Thermochemical Catalysis" Abstract: Frontier challenges in sustainability require precision control of catalysis occurring at solid-liquid interfaces. Unlike for gas-solid interfaces, at all solid–liquid interfaces, the exchange of ions and/or electrons with the solution can lead to electrostatic charging or polarization of the […]