Professor Brenda Rubenstein, Brown University “Predicting the Relative Populations of Protein Conformations without a Physics Engine Using AlphaFold 2” For decades, the conventional way to predict the different conformations of proteins and their relative populations has been to use relatively expensive physics-based algorithms such as molecular dynamics. However, in recent years, an increasing number of […]

Professor Masha Kamenetska, Boston University “Recent Developments in Single Molecule Conductance Spectroscopy” Techniques for forming and quantifying electron transport through single molecule-metal junctions have advanced in recent years.  The implications of such measurements go beyond single molecule electronics and include chemical fingerprinting of metal-molecule interface atomic structure, quantum sensing and development of surface chemistry techniques. […]

Professor Jared Lewis , Indiana University "Non-Native Enzyme Catalysis” Metalloenzymes perform some of the most remarkable transformations in nature under ambient conditions in complex cellular milieu, but their native reactivity is limited to biologically relevant reactions. Non-native enzyme catalysis brings the exquisite selectivity of enzymes to bear on chemical reactions that did not happen to […]

Professor Alexandra Velian , University of Washington "Molecular Insights into Metal-Support Interactions for Catalyst Design” A central research goal in the Velian group is to create next-generation single atom catalysts poised to harness the cooperativity between the active site and chemically non-innocent supports. To emulate defect sites in inorganic heterogeneous catalysts in a controlled fashion, […]