“Reaction of Nitroxyl (HNO) with Hydrogen Sulfide and Hydropersulfides” Zarenkiewicz, J.; Khodade, V. S.; Toscano, J. P. J. Org. Chem. 2021, 86, 868-877
“Predicting the Possible Physiological/Biological Utility of the Hydropersulfide Functional Group Based on Its Chemistry: Similarities Between Hydropersulfides and Selenols” Fukuto, J. M.; Lin, J.; Khodade, V. S.; Toscano, J. P. Antioxid. Redox Signal. 2020, 33, 1295-1307
“The reactions of hydropersulfides (RSSH) with myoglobin” Álvarez, L.; Suarez Vega, V.; McGinity, C.; Khodade, V. S.; Toscano, J. P.; Nagy, P.; Lin, J.; Works, C.; Fukuto, J. M.; Arch. Biochem. Biophys. 2020, 687, 108391
“Alkylamine-Substituted Perthiocarbamates: Dual Precursors to Hydropersulfide and Carbonyl Sulfide with Cardioprotective Actions” Khodade, V. S.; Pharoah, B. M.; Paolocci, N.; Toscano, J. P. J. Am. Chem. Soc. 2020, 142 (9), 4309-4316
“Nitroxyl (HNO) targets phospholamban cysteines 41 and 46 to enhance cardiac function” Keceli, G.; Majumdar, A.; Thorpe, C. N.; Jun, S.; Tocchetti, C. G.; Lee, D. I.; Mahaney, J. E.; Paolocci, N.; Toscano, J. P. J. Gen. Physiol. 2019, 151 (6), 758–770
“Speciation of reactive sulfur species and their reactions with alkylating agents: do we have any clue about what is present inside the cell?” Bogdandi, V.; Ida, T.; Sutton, T. R.; Bianco, C.; Ditroi, T.; Koster, G.; Henthorn, H. A.; Minnion, M.; Toscano, J. P.; van der Vliet, A.; Pluth, M. D.; Feelisch, M.; Fukuto, J. M.; Akaike, T.; Nagy, P. Br. J. Pharmacol. 2019, 176, 646-670
“The Reaction of Hydrogen Sulfide with Disulfides: Formation of a Stable Trisulfide and Implications to Biological Systems” Bianco, C. L.; Akaike, T.; Ida, T.; Nagy, P.; Bogdandi, V.; Toscano, J. P.; Kumagai, Y.; Henderson, C. F.; Goddu, R. N.; Lin, J.; Fukuto, J. M. Br. J. Pharmacol. 2019, 176, 671-683
“Development of S-Substituted Thioisothioureas as Efficient Hydropersulfide Precursors” Khodade, V.; Toscano, J. P. J. Am. Chem. Soc. 2018, 140, 17333-17337
“Amphiphilic Copolymers Capable of Concomitant Release of HNO and Small Molecule Organics” Church, D.C.; Nourian, S.; Lee, C.; Yakelis, N. A.; Toscano, J. P.; Boydston, A. J. ACS Macro Lett. 2017, 6, 46-49
“Chemical Biology of Hydropersulfides and Related Species: Possible Rolles in Cellular Protection and Redox Signaling” Alvarez, L.; Bianco, C. L.; Toscano, J. P.; Lin, J.; Akaike, T.; Fukuto, J. M. Antioxid. Redox Signal. 2017, 27, 622-633
“The chemical biology of HNO signaling” Bianco, Christopher L.; Toscano, J. P.; Bartberger, Michael D.; Fukuto, Jon M. Arch. Biochem. Biophys. 2017, 617, 129-136
“Development of N-Substituted Hydroxamic Acids with Pyrazolone Leaving Groups as Nitrosocarbonyl Precursors” Nourian, Saghar; Zilber, Zachary A.; Toscano, J. P. J. Org. Chem. 2016, 81, 9138-9146
“Nitrosocarbonyl release from O-substituted hydroxamic acids with pyrazolone leaving groups” Nourian, Saghar; Lesko, Robert P.; Guthrie, Daryl A.; Toscano, J. P. Tetrahedron 2016, 72, 6037-6042
“Selenols are resistant to irreversible modification by HNO” Bianco, Christopher L.; Moore, Cathy D.; Fukuto, Jon M.; Toscano, J. P. Free Radic. Biol. Med. 2016, 99, 71-78
“The chemical biology of the persulfide (RSSH)/perthiyl (RSS•) redox couple and possible role in biological redox signaling” Bianco, Christopher L.; Chavez, Tyler A.; Sosa, Victor; Saund, Simran S.; Nguyen, Q. Nhu N.; Tantill, Dean J.; Ichimura, Andrew S.; Toscano, J. P.; Fukuto, Jon M. Free Radic. Biol. Med. 2016, 101, 20-31
“Time-resolved Infrared (TRIR) Studies of Oxycarbonylnitrenes” Chavez, Tyler A.; Liu, Younglin; Toscano, J. P. J. Org. Chem. 2016, 81, 6320-6328
“Curtailing the Hydroxylaminobarbituric Acid – Hydantoin Rearrangement to Favor HNO Generation” Guthrie, D. A.; Nourian, S.; Takahashi, C. G.; Toscano, J. P. J. Org. Chem. 2015, 80, 1349-1356.
Featured Article: “Catch and Release of HNO with Pyrazolones” Guthrie, D. A.; Ho, A.; Takahashi, C. G.; Collins, A.; Morris, M.; Toscano, J. P. J. Org. Chem. 2015, 80, 1338-1348.
“Comparison of HNO Reactivity with Tryptophan and Cysteine in Small Peptides” Keceli, G.; Toscano, J. P. Bioorg. Med. Chem. Lett. 2014, 24, 3710-3713.
“Trans-Cis Isomerization of Vinylketones through Triplet 1,2-Biradicals” Upul Ranaweera, R. A. A.; Scott, T.; Li, Q.; Rajam, S.; Duncan, A.; Li, R. Evans, A. S.; Bohne, C.; Toscano, J. P.; Ault, B. S.; Gudmundsdottir, A. D. J. Phys. Chem. A 2014, 118, 10433-10447.
“Reactivity of C-terminal Cysteines with HNO” Keceli, G.; Toscano, J. P. Biochemistry 2014, 53, 3689-3698.
“Post-Study Caffeine Administration Enhances Memory Consolidation in Humans” Borota, D.; Murray, E.; Keceli, G.; Chang, A.; Watabe, J. M.; Ly, M.; Toscano, J. P.; Yassa, M. A. Nature Neurosci. 2014, 17, 201-203.
“2-Diazo-1-(4-hydroxyphenyl)ethanone: A Versatile Photochemical and Synthetic Reagent” Senadheera, S.; Evans, A. S.; Toscano, J. P.; Givens, R. S. Photochem. Photobiol. Sci. 2014, 13, 324-341.
“HNO Enhances SERCA2a Activity and Cardiomyocyte Function by Promoting Redox-Dependent Phospholamban Oligomerization” Sivakumaran, V.; Stanley, B. A.; Tocchetti, C. G.; Ballin, J. D.; Caceres, V.; Zhou, L.; Keceli, G.; Rainer, P. P.; Lee, D. I.; Huke, S.; Ziolo, M. T.; Kranias, E. G.; Toscano, J. P.; Wilson, G. M.; O’Rourke, B.; Kass, D. A.; Mahaney, J. E.; Paolocci, N. Antiox. Redox Signal. 2013, 19, 1185-1197.
“NMR Detection and Study of Hydrolysis of HNO-Derived Sulfinamides” Keceli, G.; Moore, C. D.; Labonte, J. W.; Toscano, J. P. Biochemistry 2013, 52, 7387-7396.
“Oxidation of N-hydroxy-L-arginine by Hypochlorous Acid to Form Nitroxyl (HNO)” Cline, M. R.; Chavez, T.A.; Toscano, J. P. J. Inorg. Biochem. 2013, 118, 148-154.
“Nanosecond Time-Resolved IR Study of Thiobenzoylnitrene” Liu, Y.; Evans, A. S.; Toscano, J. P. Phys. Chem. Chem. Phys. 2012, 14, 10438-10444.
“Reactivity of Nitroxyl-Derived Sulfinamides” Keceli, G.; Toscano, J. P. Biochemistry 2012, 51, 4206-4216.
“Development of N-Substituted Hydroxylamines as Efficient Nitroxyl (HNO) Donors” Guthrie, D. A.; Kim, N. Y.; Siegler, M. A.; Moore, C. D.; Toscano, J. P. J. Am. Chem. Soc. 2012, 134, 1962-1965.
“Optimization of HNO Production from N,O-bis-Acylated Hydroxylamine Derivatives” Sutton, A. D.; Williamson, M.; Weismiller, H.; Toscano, J. P. Org. Lett. 2012, 14, 472-475.