Congratulations to Marco Jacinto of the Greenberg group on his publication in the Journal of the American Chemical Society in collaboration with Professor Fried!
Marco reports that a commonly formed DNA lesion that is produced by cytotoxic agents is transformed into a reactive, histone post-translational modification in cells. This observation supports the possibility that the initial chemical event need not be the only source of consequences that DNA damage has on cells.
To read more, go to: https://doi.org/10.1021/jacs.2c02880