Organic chemistry at JHU bridges both synthetic and physical organic chemistry. Current activities include research in synthetic methodology, materials, natural products, medicinal chemistry, and chemical biology. Our recent research has found application in medicine (Lectka, Toscano), biology (Greenberg, Rokita, Townsend), and materials science (Klausen, Tovar).
Groups: Greenberg, Huang, Klausen, Lectka, Rokita, Toscano, Tovar, Townsend
Group Highlights
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Metal Ion-Induced Large Fragment Deactivation
Complex natural product functionalizations generally involve the use of highly engineered reagents, catalysts, or enzymes to achieve site-selectivity by lowering a selected transition state energy. We invert this strategy by […]
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Linear and Radial Conjugation in Extended π-Electron Systems
We describe the synthesis and electronic properties of new π-conjugated small molecules and polymers that combine the linear intramolecular conjugation pathways commonly associated with organic electronic materials with the emerging […]
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Development of a penem antibiotic against Mycobacteroides abscessus
Pulmonary disease caused by Mycobacteriodes abscessus has outpaced tuberculosis in the U.S., with cure rates below 50 percent. This sparked collaboration between the Townsend Research Lab and two School of […]
